Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747509Generated: October 31, 2026

Hydrochloric Acid → N-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-4-(trifluoromethoxy)aniline

https://huagongshe.com/reaction/747509

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-Butyl 3-[4-[(benzyloxy)methyl]-2-{[4-(trifluoromethoxy)phenyl]-imino}thiazol-3(2H)-yl]propylcarbamateHCID 22350977—
ProductN-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-4-(trifluoromethoxy)anilineHCID 22350937—

Reaction Steps

The compound (137 mg) obtained in the above (3) was treated in a similar manner to in Example 9 (2) to give the title compound (133 mg) as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396842B2
Source datasetuspto-grants-2008_07
ORD IDord-5ca2abec7a644b0cb4d53daa586ac9bc
Source noteuspto-grants-2008_07