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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747511Generated: October 30, 2026

Hydrochloric Acid → N-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-5-methoxy-2-pyridinamine

https://huagongshe.com/reaction/747511

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-4-(trifluoromethoxy)anilineHCID 22350937—
Reactanttert-Butyl 3-[4-(hydroxymethyl)-2-[(5-methoxy-2-pyridyl)imino]-thiazol-3(2H)-yl]propylcarbamateHCID 22351017—
ProductN-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-5-methoxy-2-pyridinamineHCID 22351036—

Reaction Steps

The compound (283 mg) obtained in the above (1) was treated in a similar manner to in Example 208 (3), (4) to give the title compound (128 mg) as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396842B2
Source datasetuspto-grants-2008_07
ORD IDord-ed1066877f764c78ac8aa7627af7b863
Source noteuspto-grants-2008_07