HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-[3-(3-Aminopropyl)-4-{[(4-chlorobenzyl)(methyl)amino]methyl}-thiazol-2(3H)-ylidene]-4-(trifluoromethoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 3-[4-{[(4-chlorobenzyl)(methyl)amino]methyl}-2-{[4-(trifluoromethoxy)phenyl]imino}thiazol-3(2H)-yl]propylcarbamate | HCID 22350950 | — |
| Product | N-[3-(3-Aminopropyl)-4-{[(4-chlorobenzyl)(methyl)amino]methyl}-thiazol-2(3H)-ylidene]-4-(trifluoromethoxy)aniline | HCID 23131537 | — |
Reaction Steps
The compound (80 mg) obtained in the above (1) was treated in a similar manner to in Example 9 (2) to give the title compound (83 mg) as hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396842B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-7f2db7e260784f4b88b83b7b5b66469e |
| Source note | uspto-grants-2008_07 |