Hydrochloric Acid → HCID 178512979, compound
Reaction equation
C(OC([NH:8][C:9]([NH:18][CH2:19][CH2:20][CH2:21][N:22]1[C:26]([C:27]2[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=2)=[CH:25][S:24][C:23]1=[N:34][C:35]1[CH:40]=[CH:39][C:38]([F:41])=[CH:37][CH:36]=1)=[N:10]C(OC(C)(C)C)=O)=O)(C)(C)C.Cl>>[F:33][C:30]1[CH:31]=[CH:32][C:27]([C:26]2[N:22]([CH2:21][CH2:20][CH2:19][NH:18][C:9]([NH2:10])=[NH:8])[C:23](=[N:34][C:35]3[CH:40]=[CH:39][C:38]([F:41])=[CH:37][CH:36]=3)[S:24][CH:25]=2)=[CH:28][CH:29]=1Participants
3
Procedure
The compound (1.12 g) obtained in the above (1) was treated in a similar manner to in Example 9 (2) to give the title compound (905 mg) as hydrochloride.
Sources & evidence
- ORD record
- ord-ee8e739389ff4ea48406cb0cd4d15b71
- Source dataset
- uspto-grants-2008_07
- Patent number
- US07396842B2
Reaction notes
Loading…