Hydrochloric Acid → HCID 22350987, compound

HRID 747517Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]2[N:13]([CH2:14][CH2:15][CH2:16][N:17]([CH2:25][CH2:26][OH:27])C(=O)OC(C)(C)C)[C:12]([C:28]3[CH:33]=[CH:32][C:31]([F:34])=[CH:30][CH:29]=3)=[CH:11][S:10]2)=[C:4]([O:35][CH3:36])[CH:3]=1.Cl>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]2[N:13]([CH2:14][CH2:15][CH2:16][NH:17][CH2:25][CH2:26][OH:27])[C:12]([C:28]3[CH:29]=[CH:30][C:31]([F:34])=[CH:32][CH:33]=3)=[CH:11][S:10]2)=[C:4]([O:35][CH3:36])[CH:3]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 86600949HCID 86600949, compound

Product 1

HCID 22350987HCID 22350987, compound

Procedure

The compound (850 mg) obtained in the above (2) was treated in a similar manner to in Example 9 (2) to give the title compound (758 mg) as hydrochloride.

Sources & evidence

ORD record: ord-b0f1d2f062c7425ab4a0154243553e4c
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07396842B2

Reaction notes

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