Hydrochloric Acid → HCID 22350986, compound

HRID 747518Notes

Reaction equation

HRID 747518 reaction equation
C(OC([N:8]([CH2:16][CH2:17][CH2:18][N:19]1[C:23]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:22][S:21][C:20]1=[N:31][C:32]1[CH:37]=[CH:36][C:35]([Cl:38])=[CH:34][C:33]=1[O:39][CH3:40])[CH2:9][CH2:10][C:11](OCC)=[O:12])=O)(C)(C)C.ClC1C=CC(N=C2N(CCCNCCO)C(C3C=CC(F)=CC=3)=CS2)=C(OC)C=1.Cl>>[Cl:38][C:35]1[CH:36]=[CH:37][C:32]([N:31]=[C:20]2[N:19]([CH2:18][CH2:17][CH2:16][NH:8][CH2:9][CH2:10][CH2:11][OH:12])[C:23]([C:24]3[CH:25]=[CH:26][C:27]([F:30])=[CH:28][CH:29]=3)=[CH:22][S:21]2)=[C:33]([O:39][CH3:40])[CH:34]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 22350987HCID 22350987, compoundHCID 22351033HCID 22351033, compound

Product 1

HCID 22350986HCID 22350986, compound

Procedure

The compound (1.3 g) obtained in the above (1) was treated in a similar manner to in Example 321 (2), (3) to give the title compound (889 mg) as hydrochloride.

Sources & evidence

ORD record
ord-79295fe2b8624cd8913381bbabe44977
Source dataset
uspto-grants-2008_07
Patent number
US07396842B2

Reaction notes

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