Hydrochloric Acid → HCID 22350943, compound

HRID 747520Notes

Reaction equation

C(OC([N:8]([CH2:13][CH2:14][CH2:15][N:16]1[C:20]([C:21]2[CH:26]=[CH:25][C:24]([F:27])=[CH:23][CH:22]=2)=[CH:19][S:18][C:17]1=[N:28][C:29]1[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][C:30]=1[O:36][CH3:37])[CH2:9][C:10]([OH:12])=[O:11])=O)(C)(C)C.Cl>>[Cl:35][C:32]1[CH:33]=[CH:34][C:29]([N:28]=[C:17]2[N:16]([CH2:15][CH2:14][CH2:13][NH:8][CH2:9][C:10]([OH:12])=[O:11])[C:20]([C:21]3[CH:22]=[CH:23][C:24]([F:27])=[CH:25][CH:26]=3)=[CH:19][S:18]2)=[C:30]([O:36][CH3:37])[CH:31]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 22350974HCID 22350974, compound

Product 1

HCID 22350943HCID 22350943, compound

Procedure

The compound (665 mg) obtained in the above (1) was treated in a similar manner to in Example 9 (2) to give the title compound (577 mg) as hydrochloride.

Sources & evidence

ORD record: ord-05ce2e21d4be4b918e8103576179cc60
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07396842B2

Reaction notes

Loading…