Hydrochloric Acid → HCID 23131536, compound

HRID 747521Notes

Reaction equation

C(OC([N:8]([CH2:14][CH2:15][CH2:16][N:17]1[C:21]([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=2)=[CH:20][S:19][C:18]1=[N:29][C:30]1[CH:35]=[CH:34][C:33]([Cl:36])=[CH:32][C:31]=1[O:37][CH3:38])[CH2:9][CH2:10][C:11]([OH:13])=[O:12])=O)(C)(C)C.Cl>>[Cl:36][C:33]1[CH:34]=[CH:35][C:30]([N:29]=[C:18]2[N:17]([CH2:16][CH2:15][CH2:14][NH:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])[C:21]([C:22]3[CH:23]=[CH:24][C:25]([F:28])=[CH:26][CH:27]=3)=[CH:20][S:19]2)=[C:31]([O:37][CH3:38])[CH:32]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 22350945HCID 22350945, compound

Product 1

HCID 23131536HCID 23131536, compound

Procedure

The compound (700 mg) obtained in the above (1) was treated in a similar manner to in Example 9 (2) to give the title compound (588 mg) as hydrochloride.

Sources & evidence

ORD record: ord-a6df35bec6a14a7a91b99a5e50fb07f1
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07396842B2

Reaction notes

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