Hydrochloric Acid → HCID 22350973, compound
Reaction equation
C(OC([N:8]([CH2:13][CH2:14][CH2:15][N:16]1[C:20]([C:21]2[CH:26]=[CH:25][C:24]([N:27]3[CH2:32][CH2:31][O:30][CH2:29][CH2:28]3)=[CH:23][CH:22]=2)=[CH:19][S:18][C:17]1=[N:33][C:34]1[CH:39]=[CH:38][C:37]([F:40])=[CH:36][CH:35]=1)[CH2:9][C:10]([OH:12])=[O:11])=O)(C)(C)C.Cl>>[F:40][C:37]1[CH:36]=[CH:35][C:34]([N:33]=[C:17]2[N:16]([CH2:15][CH2:14][CH2:13][NH:8][CH2:9][C:10]([OH:12])=[O:11])[C:20]([C:21]3[CH:26]=[CH:25][C:24]([N:27]4[CH2:28][CH2:29][O:30][CH2:31][CH2:32]4)=[CH:23][CH:22]=3)=[CH:19][S:18]2)=[CH:39][CH:38]=1Participants
3
Procedure
The compound (30 mg) obtained in the above (2) was treated in a similar manner to in Example 9 (2) to give the title compound (31 mg) as hydrochloride.
Sources & evidence
- ORD record
- ord-a8539fed188d4dac88def5ed7e1d0b2b
- Source dataset
- uspto-grants-2008_07
- Patent number
- US07396842B2
Reaction notes
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