Hydrochloric Acid → HCID 22350944, compound

HRID 747524Notes

Reaction equation

C(OC([N:8]([CH2:16][CH2:17][CH2:18][N:19]1[C:23]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:22][S:21][C:20]1=[N:31][C:32]1[CH:37]=[CH:36][C:35]([Cl:38])=[CH:34][C:33]=1[O:39][CH3:40])[CH2:9][CH2:10][O:11][CH2:12][C:13]([OH:15])=[O:14])=O)(C)(C)C.Cl>>[Cl:38][C:35]1[CH:36]=[CH:37][C:32]([N:31]=[C:20]2[N:19]([CH2:18][CH2:17][CH2:16][NH:8][CH2:9][CH2:10][O:11][CH2:12][C:13]([OH:15])=[O:14])[C:23]([C:24]3[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=3)=[CH:22][S:21]2)=[C:33]([O:39][CH3:40])[CH:34]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 22350963HCID 22350963, compound

Product 1

HCID 22350944HCID 22350944, compound

Procedure

The compound (750 mg) obtained in the above (2) was treated in a similar manner to in Example 9 (2) to give the title compound (579 mg) as hydrochloride.

Sources & evidence

ORD record: ord-997a091ded4d4a7d8c4aa09bd55a8558
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07396842B2

Reaction notes

Loading…