Hydrochloric Acid → HCID 59749211, compound

HRID 747526Notes

Reaction equation

C(OC([N:8]([CH2:15][CH2:16][CH2:17][N:18]1[C:22]([C:23]2[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=2)=[CH:21][S:20][C:19]1=[N:30][C:31]1[CH:36]=[CH:35][C:34]([Cl:37])=[CH:33][C:32]=1[O:38][CH3:39])[CH2:9][C:10]([NH:12][CH2:13][CH3:14])=[O:11])=O)(C)(C)C.Cl>>[Cl:37][C:34]1[CH:35]=[CH:36][C:31]([N:30]=[C:19]2[N:18]([CH2:17][CH2:16][CH2:15][NH:8][CH2:9][C:10]([NH:12][CH2:13][CH3:14])=[O:11])[C:22]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)=[CH:21][S:20]2)=[C:32]([O:38][CH3:39])[CH:33]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 59749217HCID 59749217, compound

Product 1

HCID 59749211HCID 59749211, compound

Procedure

The compound (900 mg) obtained in the above (1) was treated in a similar manner to in Example 9 (2) to give the title compound (850 mg) as hydrochloride.

Sources & evidence

ORD record: ord-bc5b55d4c7d74f0e86faa515e366f276
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07396842B2

Reaction notes

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