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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747577Generated: October 26, 2026

5-(Methoxycarbonyl)thiophene-2-carboxylic acid → 5-[1-(5-Bromo-thiophen-2-yl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/747577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methoxycarbonyl)thiophene-2-carboxylic acidHCID 818352—
Reactant1-(5-Bromothiophen-2-yl)ethan-1-amineHCID 4359396—
Product5-[1-(5-Bromo-thiophen-2-yl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl esterHCID 69292340—

Reaction Steps

The title compound was prepared in an analogous manner to that described in example 1, step 1 from 1-(5-bromo-thiophen-2-yl)-ethylamine and thiophene-2,5-dicarboxylic acid monomethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396944B2
Source datasetuspto-grants-2008_07
ORD IDord-403d778aa425413482b07f6a84b59747
Source noteuspto-grants-2008_07