HCID 12180674, compound → HCID 68567648, compound

HRID 747641Notes

Reaction equation

HRID 747641 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5](/[CH:9]=[CH:10]/[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:4]=1[N+:17]([O-])=O.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:4]=1[NH2:17]

Participants

5

Reactant 2

HCID 12180674HCID 12180674, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 68567648HCID 68567648, compoundYield 105.6%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2.25 g of 1-methoxy-2-nitro-3-[(E)-2-phenylvinyl]benzene are added to 0.18 g of palladium-on-charcoal (10%) suspended in 90 ml of methanol, and placed under 4 bar of hydrogen. After 18 hours, the reaction medium is filtered through talc and the filtrate is concentrated to give 2.115 g of the expected product.

Workup

  1. filtrationthe reaction medium is filtered through talc
  2. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-c85ba9d6cac945279cd0728e402c4a6a
Source dataset
uspto-grants-2008_07
Patent number
US07396958B2

Reaction notes

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