Hydrochloric Acid → Hydrochloric Acid

HRID 747657Notes

Reaction equation

HRID 747657 reaction equation
C(OC([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][CH:19]=1)[C:15]#[N:16])=O)(C)(C)C.[ClH:20]>O1CCOCC1>[ClH:20].[NH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][CH:19]=1)[C:15]#[N:16]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 109890793-(Boc-aminoethyloxy)benzonitrile

Product 2

HCID 313Hydrochloric AcidHCID 109098773-(2-Aminoethoxy)benzonitrile

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.41 g of 3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile was dissolved in 20 ml of 4 N solution of hydrogen chloride in dioxane, and the solution was stirred at room temperature for 2 hours. The solvent was evaporated. The residue was suspended in dichloromethane, and the obtained suspension was filtered to obtain hydrochloride of the title compound.

Workup

  1. customThe solvent was evaporated
  2. filtrationthe obtained suspension was filtered

Sources & evidence

ORD record
ord-f74dfe6789bf4863afe4df574c3ab225
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Reaction notes

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