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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747668Generated: October 25, 2026

Hydrochloric Acid → 4-(2-Imidazoline-2-yl)benzoic acid hydrochloride

https://huagongshe.com/reaction/747668

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactantethyl 4-(4,5-dihydro-1H-imidazol-2-yl)benzoateHCID 22709787—
SolventAcetic AcidHCID 176—
Product4-(2-Imidazoline-2-yl)benzoic acid hydrochlorideHCID 68831143—

Reaction Steps

1 g (4.58 mmol) of ethyl 4-(2-imidazoline-2-yl)benzoate was heated under reflux in 4 ml of hydrochloric acid and 8 ml of acetic acid. The solvent was evaporated to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396844B1
Source datasetuspto-grants-2008_07
ORD IDord-fa421e5c1a2b457d9d5c2768b0f7a803
Source noteuspto-grants-2008_07