Hydrochloric Acid → 4-(2-Imidazoline-2-yl)benzoic acid hydrochloride

HRID 747668Notes

Reaction equation

HRID 747668 reaction equation
[NH:1]1[CH2:5][CH2:4][N:3]=[C:2]1[C:6]1[CH:16]=[CH:15][C:9]([C:10]([O:12]CC)=[O:11])=[CH:8][CH:7]=1.[ClH:17]>C(O)(=O)C>[ClH:17].[NH:3]1[CH2:4][CH2:5][N:1]=[C:2]1[C:6]1[CH:7]=[CH:8][C:9]([C:10]([OH:12])=[O:11])=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22709787ethyl 4-(4,5-dihydro-1H-imidazol-2-yl)benzoate

Product 1

HCID 688311434-(2-Imidazoline-2-yl)benzoic acid hydrochloride

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1 g (4.58 mmol) of ethyl 4-(2-imidazoline-2-yl)benzoate was heated under reflux in 4 ml of hydrochloric acid and 8 ml of acetic acid. The solvent was evaporated to obtain the title compound.

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-fa421e5c1a2b457d9d5c2768b0f7a803
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Reaction notes

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