Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1-(Pyridin-4-yl)piperidine-4-carboxylic acid hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate | HCID 9899468 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 1-(Pyridin-4-yl)piperidine-4-carboxylic acid hydrochloride | HCID 16217269 | — |
반응 단계
2.95 g (12.6 mmol) of ethyl 1-(4-pyridyl)piperidine-4-carboxylate was stirred in 100 ml of dioxane. 50 ml of 1 N aqueous hydrochloric acid solution was added thereto, and the resultant mixture was stirred at 95° C. for 20 hours. The solvent was evaporated under reduced pressure to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07396844B1 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-f968195bc6e14ea7a4c15b2f96988c19 |
| 출처 메모 | uspto-grants-2008_07 |