HCID 17788760, compound → 3-(3-Cyanophenoxy)propanoic acid

HRID 747717Notes

Reaction equation

HRID 747717 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:13]=[CH:14][CH:15]=1)[O:6][CH2:7][CH2:8][C:9]([O:11]C)=[O:10])#[N:2]>Cl>[C:1]([C:3]1[CH:4]=[C:5]([CH:13]=[CH:14][CH:15]=1)[O:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10])#[N:2]

Participants

3

Reactant 1

HCID 17788760HCID 17788760, compound

Product 1

HCID 177890543-(3-Cyanophenoxy)propanoic acid

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

500 mg (2.4 mmol) of methyl 3-(3-cyanophenoxy)propionate was heated in 40 ml of 6 N hydrochloric acid at 70° C. for 30 minutes. After the extraction with ethyl acetate, the extract was washed with saturated aqueous NaCl solution and then dried on anhydrous magnesium sulfate. The solvent was evaporated to obtain the title compound.

Workup

  1. extractionAfter the extraction with ethyl acetate
  2. washthe extract was washed with saturated aqueous NaCl solution
  3. dry with materialdried on anhydrous magnesium sulfate
  4. customThe solvent was evaporated

Sources & evidence

ORD record
ord-a0f90bcfe61f4b89968b8c87665793a1
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Reaction notes

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