Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | HCID 53980250 | HCID 53980250 | — |
| Catalyst | Copper(1+) | HCID 104815 | — |
| Product | HCID 54463448 | HCID 54463448 | — |
Reaction Steps
300 mg (0.84 mmol) of 3-[2-(4-bromobenzenesulfonylamino)ethoxy]benzonitrile was dissolved in 1 ml of N-methylpyrrolidone. 76 mg (0.84 mmol) of copper (I) cyamide was added to the solution, and they were stirred at 140° C. overnight. The crude product was obtained by the treatment with ethyl acetate as the extractant in an ordinary manner. After the silica gel column chromatography, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07396844B1 |
|---|
| Source dataset | uspto-grants-2008_07 |
|---|
| ORD ID | ord-e74e2d9a73c04a328a51d079d74c9758 |
|---|
| Source note | uspto-grants-2008_07 |
|---|
