Sulfuric Acid → HCID 21962143, compound

HRID 747833Notes

Reaction equation

HRID 747833 reaction equation
C([O:3][C:4](=O)[CH2:5][C:6](=[O:14])[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1)C.C[NH:17][C:18](=[NH:20])S.OS(O)(=O)=O>>[NH2:20][C:18]1[O:14][C:6]([C:7]2[CH:8]=[CH:9][C:10]([Cl:13])=[CH:11][CH:12]=2)=[CH:5][C:4](=[O:3])[N:17]=1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 101336Ethyl 3-(4-chlorophenyl)-3-oxopropanoateHCID 178485201HCID 178485201, compound

Product 1

HCID 21962143HCID 21962143, compound

Procedure

The title compound was prepared from ethyl(4-chloro)benzoylacetate (5.0 g, 22 mmol) (obtained in preparation 2) and methylthiopseudourea.H2SO4 (3.31 g, 12 mmol) by following the procedure described in preparation 4, (0.573 g, 11.6%). MS m/z: 223 (M+).

Workup

  1. customdescribed in preparation 4, (0.573 g, 11.6%)

Sources & evidence

ORD record
ord-e1855d6e591343c1a674b647aeb18b96
Source dataset
uspto-grants-2008_07
Patent number
US07399760B2

Reaction notes

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