HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-benzyl-3-oxopiperazine-1-carboxylate → 1-Benzylpiperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-benzyl-3-oxopiperazine-1-carboxylate | HCID 59750509 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Benzylpiperazin-2-one | HCID 1514303 | — |
Reaction Steps
A mixture of benzyl 4-benzyl-3-oxopiperazine-1-carboxylate (4.7 g, 14.5 mmol) and 10% Pd/C (0.47 g) in ethanol (150 mL) was stirred under an atmosphere of hydrogen (1 atm) at room temperature overnight. The product mixture was filtered through a pad of Celite, and concentrated under vacuum to provide 1-benzylpiperazin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07399763B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-4a1ffa1f52fa4eb2bbb730eae986d1e3 |
| Source note | uspto-grants-2008_07 |