Piperidine → HCID 59750613, compound

HRID 747881Notes

Reaction equation

HRID 747881 reaction equation
Cl[CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[C:20]([C:21]3[CH:22]=[CH:23][C:24]([O:27][CH3:28])=[N:25][CH:26]=3)=[C:19]([CH3:29])[C:18]3[C:13](=[CH:14][C:15]([O:30]COCC[Si](C)(C)C)=[CH:16][CH:17]=3)[O:12]2)=[CH:7][CH:6]=1.[NH:39]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1>>[CH3:28][O:27][C:24]1[N:25]=[CH:26][C:21]([C:20]2[CH:11]([C:8]3[CH:7]=[CH:6][C:5]([O:4][CH2:3][CH2:2][N:39]4[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]4)=[CH:10][CH:9]=3)[O:12][C:13]3[C:18]([C:19]=2[CH3:29])=[CH:17][CH:16]=[C:15]([OH:30])[CH:14]=3)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 11592086HCID 11592086, compound

Product 1

HCID 59750613HCID 59750613, compound

Procedure

The title product was prepared as a white solid according to the procedure described in Example 34 using 5-[2-[4-(2-chloro-ethoxy)-phenyl]-4-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-2H-chromen-3-yl]-2-methoxy-pyridine and piperidine as the starting material.

Sources & evidence

ORD record
ord-57bafdd506d346718bd0bc42e34f9463
Source dataset
uspto-grants-2008_07
Patent number
US07399767B2

Reaction notes

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