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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 748027Generated: October 30, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-Methyl-6-[3-(5-methyl-2-phenyloxazol-4-ylmethoxy)cyclohexyloxymethyl]benzoic Acid

https://huagongshe.com/reaction/748027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant4-(Iodomethyl)-5-methyl-2-phenyl-1,3-oxazoleHCID 22493658—
Product2-Methyl-6-[3-(5-methyl-2-phenyloxazol-4-ylmethoxy)cyclohexyloxymethyl]benzoic AcidHCID 22493660—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-phenyl-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 69 of molecular weight 435.52 (C26H29NO5), MS(ESI): 436.32 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07399777B2
Source datasetuspto-grants-2008_07
ORD IDord-2815bd93dea64c369f2b66cfd2d3916c
Source noteuspto-grants-2008_07