m-Chloroperbenzoic acid → HCID 59750439, compound

HRID 748222Notes

Reaction equation

HRID 748222 reaction equation
[CH2:1]([S:3][C:4]1[N:9]=[C:8]([C:10]2[S:11][C:12]3[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14](=[O:16])[N:15]=2)[CH:7]=[CH:6][CH:5]=1)[CH3:2].ClC1C=CC=C(C(OO)=[O:29])C=1>C(Cl)(Cl)Cl>[CH2:1]([S:3]([C:4]1[N:9]=[C:8]([C:10]2[S:11][C:12]3[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14](=[O:16])[N:15]=2)[CH:7]=[CH:6][CH:5]=1)=[O:29])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 59750393HCID 59750393, compound

Product 1

HCID 59750439HCID 59750439, compoundYield 47.9%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

2-[6-(Ethylthio)-2-pyridyl]-4H-1,3-benzothiazine-4-one (0.10 g, 0.33 mmol) was dissolved in chloroform (50 ml). A solution of 3-chloroperbenzoic acid (ca. 77%, 0.075 g, 0.33 mmol) in chloroform (10 ml) was added dropwise to the mixture, and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated and the residue was recrystallized from ethanol to give the titled compound (0.050 g, 47%) as pale yellow crystals.

Workup

  1. customThe solvent was evaporated
  2. customthe residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-c016e4df745e4536b6d69a4f24d660aa
Source dataset
uspto-grants-2008_07
Patent number
US07399759B2

Reaction notes

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