Triethylamine → HCID 59750433, compound

HRID 748360Notes

Reaction equation

HRID 748360 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([S:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[N:4]=1)#[N:2].[C:16](OC)(=[O:24])[C:17]1[C:18](=[CH:20][CH:21]=[CH:22][CH:23]=1)[SH:19].C(N(CC)CC)C>C1(C)C=CC=CC=1>[N:13]1[CH:14]=[CH:15][C:10]([S:9][C:5]2[N:4]=[C:3]([C:1]3[S:19][C:18]4[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=4[C:16](=[O:24])[N:2]=3)[CH:8]=[CH:7][CH:6]=2)=[CH:11][CH:12]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 21009Benzoic acid, 2-mercapto-, methyl esterHCID 22939261HCID 22939261, compound

Product 1

HCID 59750433HCID 59750433, compoundYield 2.1%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2-Cyano-6-(4-pyridylthio)pyridine (1.54 g, 7.22 mmol) and methyl thiosalicylate (1.34 g, 7.94 mmol) were dissolved in toluene (50 ml), and triethylamine (1.52 ml, 10.83 mmol) was added thereto. The mixture was refluxed for 18 hrs. The solvent was evaporated, and the residue was recrystallized from ethanol to give the titled compound (0.053 g, 2%) as pale yellow crystals.

Workup

  1. temperatureThe mixture was refluxed for 18 hrs
  2. customThe solvent was evaporated
  3. customthe residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-63ed61cbaad84574abc75294756c03f8
Source dataset
uspto-grants-2008_07
Patent number
US07399759B2

Reaction notes

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