1-Ethylpiperazine → HCID 822459, compound

Participants

Reaction Steps

The title compound was prepared as described for Example 25 using N-ethylpiperazine and 6-chloropyridine-3-sulfonyl chloride (described in: Naegeli, C. et al. Helv. Chim. Actal. 1938, 21, 1746-1750). Yield:83%: 1H NMR (CDCl3, 400 MHz) δ 8.75 (d, J=3 Hz, 1 H), 7.97 (dd, J=8, 3 Hz, 1 H), 7.50 (d, J=8 Hz, 1 H), 3.16-3.06 (m, 4 H), 2.60-2.46 (m, 4 H), 2.42 (q, J=7 Hz, 2 H), 1.04 (t, J=7 Hz, 3 H); 13C NMR (CDCl3, 100 MHz) δ 155.8, 148.9, 137.8, 131.3, 124.7, 51.9, 51.6, 46.0, 11.9; MS (ES) m/z 290 (M++1).

Provenance & Evidence