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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 748524Generated: October 30, 2026

5-Bromo-2-oxindole → 5-(Thiophen-2-yl)-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/748524

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-oxindoleHCID 611193—
Reactant2-(Tri-n-butylstannyl)thiopheneHCID 2779373—
Product5-(Thiophen-2-yl)-1,3-dihydro-2H-indol-2-oneHCID 16637508—

Reaction Steps

The title compound was prepared as described for Example 37 using 5-bromooxindole and tri-n-butyl(2-thienyl)tin: MS (ES) n/z 216 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07399780B2
Source datasetuspto-grants-2008_07
ORD IDord-b1dbea2658be4e349d8b8f719350789f
Source noteuspto-grants-2008_07