Trifluoroacetic acid → HCID 59750924, compound

Participants

Reaction Steps

At 0° C., trifluoroacetic acid (10 ml) was added to a methylene chloride (30 ml) solution of t-butyl 3-[(4-chlorophenyl)sulfonyl]-3-(2,5-difluorophenyl)propionate (3.10 g, 7.43 mmol). The resulting mixture was stirred at room temperature for 2 hours. To the residue obtained by concentrating the reaction mixture was added toluene and the resulting mixture was concentrated. The residue thus obtained was recrystallized from ethyl acetate-hexane, whereby the title compound (2.29 g, 85%) was obtained as colorless needle crystals.

Provenance & Evidence