反应详情

Methyl N-[(1R,3S)-3-benzyloxycarbonylaminocyclohexyl]carbamate, 19a, (1.09 g, 3.56 mmol) was dissolved in ethanol (100 mL) and treated with 10% Pd/C (0.38 g, 0.36 mmol). The flask was capped, degassed and fitted with a hydrogen balloon and allowed to stir overnight. The reaction mixture was filtered under nitrogen and concentrated in vacuo to provide the product, 19b, as a white solid.

1. customThe flask was capped
2. customdegassed
3. customfitted with a hydrogen balloon
4. filtrationThe reaction mixture was filtered under nitrogen
5. concentrationconcentrated in vacuo