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HRID749463

反应详情

EQUATION

反应方程式

HRID 749463 的结构方程式

REACTANTS

反应物

2
结构：C=CC[C@H](CN(C)C(=O)c1cc(Br)cc(I)c1)c1ccc(F)cc1
HCID68977011

未命名化合物

结构：C=CC[C@H](CN(C)C(=O)c1cc(Cl)cc(Cl)c1)c1ccc(F)cc1
HCID68978638

未命名化合物

PRODUCTS

生成物

1
结构：CN(C[C@@H](CC=O)c1ccc(F)cc1)C(=O)c1cc(Br)cc(I)c1
HCID58683521

未命名化合物

PROCEDURE

实验过程

The compound was synthesized in an analogous way to that of Method 21b but using 3-bromo-N-[(2S)-2-(4-fluorophenyl)pent-4en-1-yl]-5-iodo-N-methylbenzamide rather than 3,5-dichloro-N-[(2S)-2-(4-fluorophenyl)pent-4-en-1-yl]-N-methylbenzamide (yield, 100%). 1H NMR (500 MHz, CDCl3): 2.6-3.2 (cm, 4H), 3.4-3.9 (cm, 2H), 4.0-4.2, (cm, 2H), 6.8-8.2 (cm, 7H), 9.8 (s, 1H).

WORKUP

后处理

  1. customThe compound was synthesized in an analogous way to that of Method 21b