Hydrochloric Acid → HCID 69306516, compound

Participants

Reaction Conditions

Reaction Steps

12 mg (0.02 mmol) of ethyl 7-chloro-6-(2-chloro-4,6-difluorophenylamino)-4-oxo-1-pyridin-3-yl-1,4-dihydroquinolone-3-carboxylate were suspended in 6 ml of an ethanol/2 N sodium hydroxide solution mixture (1:1) and heated at 90° C. for 3 hours. After cooling to room temperature, the pH was adjusted to 2 with 2 N hydrochloric acid and the precipitate was filtered off with suction. 6 mg (53%) of the product were obtained.

Provenance & Evidence