HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | HCID 22235063 | HCID 22235063 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235059 | HCID 22235059 | 10% |
Reaction Steps
Using 0.50 g of (2,4,6-trifluorobenzyl)malononitrile, 10 ml of N,N-dimethylformamide, 0.11 g of sodium hydride (60% in oil), and 0.46 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.07 g of 2-(2,4,6-trifluorobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (17)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-815e43ca22d044579fcb47fd4392a62b |
| Source note | uspto-grants-2008_07 |