HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235041, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-(3,3,3-Trifluoropropyl)malononitrile | HCID 22185761 | — |
| Reactant | HCID 22235020 | HCID 22235020 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235041 | HCID 22235041 | 88.5% |
Reaction Steps
Using 0.49 g of 3-metyl-4-nitrobenzyl methanesulfonate, 5 ml of N,N-dimethylformamide, 0.10 g of sodium hydride (60% in oil), and 0.3 g of (3,3,3-trifluoropropyl)malononitrile, and according to the process described in the Production Example 26, there was obtained 0.51 g of 2-(3-methyl-4-nitrobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (45)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-546fa157cee34aabb5628ffb336390ed |
| Source note | uspto-grants-2008_07 |