1,2-Epoxybutane → HCID 23060831, compound

Participants

Reaction Steps

A solution (6 ml) of 4-methanesulfonylbenzylamine (3.0 g) and 1,2-epoxybutane (1.1 g) in 2-propanol was heated under reflux for 12 hrs. The reaction mixture was concentrated under reduced pressure, and the obtained residue was purified by silica gel column chromatography (ethyl acetate-ethyl acetate:methanol=10:1) to give the title compound (1.7 g).

Provenance & Evidence