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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750184Generated: October 25, 2026

O-Butylhydroxylamine → 6-chloro-1-oxo-4-phenyl-2-propoxy-1,2-dihydroisoquinoline-3-carboxylic Acid

https://huagongshe.com/reaction/750184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ButylhydroxylamineHCID 3014370—
Reactant6-chloro-4-phenylisocoumarin-3-carboxylic AcidHCID 10380092—
Product6-chloro-1-oxo-4-phenyl-2-propoxy-1,2-dihydroisoquinoline-3-carboxylic AcidHCID 23060546—

Reaction Steps

The present compound was synthesized by a method similar to that in Example 187 and using 6-chloro-1-oxo-4-phenyl-1H-isochromen-3-carboxylic acid and O-n-butylhydroxylamine. A colorless powder (280 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07402595B2
Source datasetuspto-grants-2008_07
ORD IDord-8efb77aab97343f8b5b773e3b368bfc1
Source noteuspto-grants-2008_07