HRID750249

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10921734

4-hydroxymethylpyridin-2-carboxylic acid isobutyl ester

C11H15NO3

结构：O=C(O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccccc1

HCID23060648

未命名化合物

PRODUCTS

生成物

结构：CC(C)COC(=O)c1cc(COC(=O)c2c(-c3ccccc3)c3cc(Br)ccc3c(=O)n2Cc2ccccc2)ccn1

HCID69155413

未命名化合物

PROCEDURE

实验过程

The present compound was synthesized by a method similar to that in Example 200 and using 2-benzyl-6-bromo-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (600 mg) and 4-hydroxymethylpyridin-2-carboxylic acid isobutyl ester. A colorless powder (530 mg).

WORKUP

后处理

customThe present compound was synthesized by a method similar to that in Example 200

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f6c37ae98dae4d82a710e75c0a4611b6
来源数据集: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07402595B2
来源说明: uspto-grants-2008_07

反应 SMILES

[CH2:1]([N:8]1[C:17]([C:18]([OH:20])=[O:19])=[C:16]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([Br:27])[CH:14]=2)[C:9]1=[O:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:29]([O:33][C:34]([C:36]1[CH:41]=[C:40]([CH2:42]O)[CH:39]=[CH:38][N:37]=1)=[O:35])[CH:30]([CH3:32])[CH3:31]>>[CH2:29]([O:33][C:34]([C:36]1[CH:41]=[C:40]([CH2:42][O:19][C:18]([C:17]2[N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[C:9](=[O:28])[C:10]3[C:15]([C:16]=2[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)=[CH:14][C:13]([Br:27])=[CH:12][CH:11]=3)=[O:20])[CH:39]=[CH:38][N:37]=1)=[O:35])[CH:30]([CH3:32])[CH3:31]