HRID750286

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11474

Piconol

C6H7NO

结构：CS(=O)(=O)c1ccc(Cn2c(C(=O)O)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1

HCID23060958

未命名化合物

PRODUCTS

生成物

结构：CS(=O)(=O)c1ccc(Cn2c(C(=O)OCc3ccccn3)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1

HCID69156877

未命名化合物

PROCEDURE

实验过程

The present compound was synthesized by a method similar to that in Example 200 and using 6-bromo-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid and 2-pyridinemethanol.

WORKUP

后处理

customThe present compound was synthesized by a method similar to that in Example 200

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-442c36e8ac0645e7b30b74a7bdcd7676
来源数据集: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07402595B2
来源说明: uspto-grants-2008_07

反应 SMILES

[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[N:7]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH3:23])(=[O:22])=[O:21])=[CH:16][CH:15]=1)[C:6]([C:24]([OH:26])=[O:25])=[C:5]2[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1.[N:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[CH2:39]O>>[N:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[CH2:39][O:25][C:24]([C:6]1[N:7]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([S:20]([CH3:23])(=[O:21])=[O:22])=[CH:18][CH:19]=2)[C:8](=[O:12])[C:9]2[C:4]([C:5]=1[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1)=[CH:3][C:2]([Br:1])=[CH:11][CH:10]=2)=[O:26]