Hydrogen chloride-ethyl acetate → HCID 23060587, compound

Participants

Reaction Steps

To [4-(3-acetyl-6-bromo-1-oxo-4-phenyl-1H-isoquinolin-2-ylmethyl)benzyl]carbamic acid tert-butyl ester (561 mg) was added 4N hydrochloric acid ethyl acetate solution (5 ml) and the mixture was stirred at room temperature for 30 min. The solvent was evaporated under reduced pressure and toluene was added. The solvent was evaporated again under reduced pressure. To the obtained residue was added diisopropyl ether and the mixture was crystallized to give the title compound (410 mg, 82%).

Provenance & Evidence