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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750333Generated: October 26, 2026

2-Benzoyl-4-chlorobenzoic acid → 4-(6-chloro-3-butyryl-1-oxo-4-phenyl-1H-isoquinolin-2-ylmethyl)benzenesulfonamide

https://huagongshe.com/reaction/750333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Benzoyl-4-chlorobenzoic acidHCID 12205290—
Reactant4-[(2-hydroxypentylamino)methyl]benzenesulfonamide HydrochlorideHCID 69157761—
Product4-(6-chloro-3-butyryl-1-oxo-4-phenyl-1H-isoquinolin-2-ylmethyl)benzenesulfonamideHCID 10152265—

Reaction Steps

In the same manner as in Example 452, Step 2, the title compound was synthesized from 4-[(2-hydroxypentylamino)methyl]benzenesulfonamide hydrochloride and 2-benzoyl-4-chlorobenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07402595B2
Source datasetuspto-grants-2008_07
ORD IDord-8312ea5defa7454aa685ab7891abf782
Source noteuspto-grants-2008_07