HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzoyl-4-chlorobenzoic acid → 4-(6-chloro-1-oxo-4-phenyl-3-propionyl-1H-isoquinolin-2-ylmethyl)benzoic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzoyl-4-chlorobenzoic acid | HCID 12205290 | — |
| Reactant | 4-[(2-Hydroxybutylamino)methyl]benzoic acid methyl ester hydrochloride | HCID 69157024 | — |
| Product | 4-(6-chloro-1-oxo-4-phenyl-3-propionyl-1H-isoquinolin-2-ylmethyl)benzoic Acid Methyl Ester | HCID 69157144 | — |
Reaction Steps
In the same manner as in Example 458, Step 2, the title compound was synthesized from 4-[(2-hydroxybutylamino)methyl]benzoic acid methyl ester hydrochloride and 2-benzoyl-4-chlorobenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402595B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-96ab53c317754273a77f5a916cb0f8cb |
| Source note | uspto-grants-2008_07 |