反应详情

A solution of 3-(3-nitrobenzyl)-7-(1-(2-(trimethylsilyl)ethoxymethyl)-1H-pyrazol-5-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine (156 mg, 0.34 mmol) in MeOH (2 mL) was treated with 4-M HCl in dioxane (4 mL) stirred at room temperature for 2 h, concentrated in vacuo, triturated with Et2O and filtered to give the title compound (110 mg, 97%) as a yellow solid.

1. concentrationconcentrated in vacuo
2. customtriturated with Et2O
3. filtrationfiltered