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1-(Bromomethyl)-3-(trifluoromethyl)benzene → {3-[1,1-Dioxo-2-(3-trifluoromethyl-benzyl)-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-2-methyl-indol-1-yl}-acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(Bromomethyl)-3-(trifluoromethyl)benzene | HCID 123061 | — |
| 反応物 | [3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid tert-butyl ester | HCID 67317115 | — |
| 生成物 | {3-[1,1-Dioxo-2-(3-trifluoromethyl-benzyl)-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-2-methyl-indol-1-yl}-acetic acid | HCID 59753801 | — |
反応手順
The title compound was prepared by the method described for example 14 using the product from example 3, step c) and 3-trifluoromethyl-benzyl bromide. MS: ESI (negative): 513 (M−H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07405215B2 |
| 出典データセット | uspto-grants-2008_07 |
| ORD ID | ord-39d35862ee7c490aaaf06d346175c089 |
| 出典メモ | uspto-grants-2008_07 |