Diethylamine → HCID 10437508, compound

Participants

Reaction Steps

2-(3,4-Difluorobenzyloxy)-4-(methylsulfonyl)-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-pyrimidine (Reference Example 7) (29 mg, 0.05 mmol) was reacted with diethylamine (38.0 mg, 0.52 mmol) by the same general procedure described in Example 103 to afford the title compound: HPLC/MS: m/e=548 (M++1); Rt=3.84 min. 1H-NMR 400 MHz (CDCl3): δ 0.96-1.00 (m, 6H), 3.20-3.30 (m, 4H), 5.30-5.40 (m, 2H), 6.90 (d, J=9 Hz, 1H), 7.01-7.21 (m, 8H), 7.35-7.40 (m, 1H).

Provenance & Evidence