(3-Methoxyphenyl)boronic acid → HCID 59753886, compound

Participants

Reaction Steps

This derivative was prepared by the method described in Example 132 using 2-(3,4-difluorophenoxy)-4-methoxy-5-trifluoromethansulfonyl-6-[2,4-dichlorophenyl]pyrimidine (53 mg, 0.1 mmol) as described in Reference Example 17 and 3-methoxybenzeneboronic acid (Lancaster, 16 mg, 0.1 mmol). HPLC Rt=4.63 min. 1H-NMR 500 MHz (CDCl3): 3.77 (s, 3H), 4.12 (s, 3H), 6.51 (m, 1H), 6.72 (m, 2H), 6.75 (m, 1H), 6.90 (dd, J=8 Hz, J=2 Hz, 1H), 7.07 (q, J=9 Hz, 1H), 7.25 (t, J=4 Hz, 1H), 7.43 (d, J=2 Hz, 2H), 7.49 (d, J=2 Hz, 1H).

Provenance & Evidence