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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750915Generated: November 2, 2026

Sodium Azide → HCID 86591700, compound

https://huagongshe.com/reaction/750915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AzideHCID 33557—
ReactantHCID 86591701HCID 86591701—
SolventDimethylformamideHCID 6228—
ProductHCID 86591700HCID 8659170088%

Reaction Conditions

Temperature70 °C

Reaction Steps

The mixture of sodium azide (26.0 mmol) and (R)-{3-[4-(4,4-dimethoxy-3,3-difluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-methanesulfonate (12.0 mmol) in dimethylformamide was heated at 70° C. for 14 hours. The reaction mixture was poured on ice cold water, and the solid was filtered to afford title compound in 88% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405228B2
Source datasetuspto-grants-2008_07
ORD IDord-a00e8298b36c4c34a732dcafc1f10f40
Source noteuspto-grants-2008_07