Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 86591701 | HCID 86591701 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86591700 | HCID 86591700 | 88% |
Reaction Steps
The mixture of sodium azide (26.0 mmol) and (R)-{3-[4-(4,4-dimethoxy-3,3-difluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-methanesulfonate (12.0 mmol) in dimethylformamide was heated at 70° C. for 14 hours. The reaction mixture was poured on ice cold water, and the solid was filtered to afford title compound in 88% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07405228B2 |
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| Source dataset | uspto-grants-2008_07 |
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| ORD ID | ord-a00e8298b36c4c34a732dcafc1f10f40 |
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| Source note | uspto-grants-2008_07 |
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