反应详情

温度

80 °C

A mixture of 500 mg 4-(4-(4-methoxy-phenyl)-butyl)-1H-[1,2,3]triazole and 1.5 ml 48% hydrobromic acid was stirred at 80° C. for 9 h. After adjustment to pH=6 by addition of conc. sodium hydroxide solution, the aqueous layer was discarded and the remaining sticky residue purified by HPLC-MS(RP18, methanol/water 7:3, pH=2.3). Yield 170 mg (36%).

1. customthe remaining sticky residue purified by HPLC-MS(RP18, methanol/water 7:3, pH=2.3)