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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751149Generated: October 26, 2026

4-Amino-2-fluoro-3-methylbenzonitrile → 2-Fluoro-4-isocyanato-3-methylbenzonitrile

https://huagongshe.com/reaction/751149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-fluoro-3-methylbenzonitrileHCID 45078676—
Reactant4-Isocyanato-5,6,7,8-tetrahydronaphthalene-1-carbonitrileHCID 59754304—
Product2-Fluoro-4-isocyanato-3-methylbenzonitrileHCID 59754317—

Reaction Steps

2-Fluoro-4-isocyanato-3-methylbenzonitrile was prepared from 4-amino-2-fluoro-3-methyl-benzonitrile (72D) following a procedure analogous to the procedure used in the preparation of compound 2E (Example 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405234B2
Source datasetuspto-grants-2008_07
ORD IDord-95ef61e937a94324b717bbb350585c08
Source noteuspto-grants-2008_07