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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751192Generated: October 25, 2026

Tetrabutylammonium Fluoride → ethyl (4-hydroxy-1H-indol-1-yl)acetate

https://huagongshe.com/reaction/751192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
ReactantHCID 68822793HCID 68822793—
SolventTetrahydrofuranHCID 8028—
Productethyl (4-hydroxy-1H-indol-1-yl)acetateHCID 68822476—

Reaction Steps

In analogy to the procedure described in example 1 c], [4-(tert-butyl-dimethyl-silanyloxy)-indol-1-yl]-acetic acid ethyl ester was treated with tetrabutylammonium fluoride in THF to give the title compound as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405236B2
Source datasetuspto-grants-2008_07
ORD IDord-1bd91f1d65a64895801507d8e6695a90
Source noteuspto-grants-2008_07