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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751209Generated: October 25, 2026

Lithium Hydroxide → {6-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynylamino]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/751209

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{6-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynylamino]-indol-1-yl}-acetic acid ethyl esterHCID 68823310—
Product{6-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynylamino]-indol-1-yl}-acetic acidHCID 11697350—

Reaction Steps

In analogy to the procedure described for example 1 e], {6-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynylamino]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as green solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405236B2
Source datasetuspto-grants-2008_07
ORD IDord-4246f5c6cf174b839e0f050aac8010ef
Source noteuspto-grants-2008_07