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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751215Generated: October 26, 2026

1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate → (7-Hydroxy-indol-1-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/751215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Butanaminium, N,N,N-tributyl-, fluoride, hydrateHCID 16211673—
Reactant[7-(tert-Butyl-dimethyl-silanyloxy)-indol-1-yl]-acetic acid ethyl esterHCID 68824002—
Product(7-Hydroxy-indol-1-yl)-acetic acid ethyl esterHCID 68821713—

Reaction Steps

In analogy to the procedure described in example 6 c], [7-(tert-butyl-dimethyl-silanyloxy)-indol-1-yl]-acetic acid ethyl ester was treated with tetrabutylammonium fluoride hydrate to give the title compound as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405236B2
Source datasetuspto-grants-2008_07
ORD IDord-3367a52c6b8f43d4985446b56cff5a77
Source noteuspto-grants-2008_07